ABSTRACT
Zinc deficiency is characterized by acrodermatitis enteropathica like eruption such as periorificial dermatitis, diarrhea and mental irritability. This syndrome occurs due to decreased supplementation, increased consumption or decreased bowel absorption of zinc. We report here on a case of acquired zinc deficiency in a patient who was receiving total parenteral nutrition due to ischemic colitis. She showed denuded patches on the perinasal, perioral and perineal area and tense bullae on both hands. She was suffering from diarrhea and mental irritability. Her blood zinc level was 4.9microng/dl. Subsequent intravenous zinc supplementation cleared up her clinical manifestations.
Subject(s)
Humans , Absorption , Acrodermatitis , Blister , Colitis, Ischemic , Dermatitis , Diarrhea , Hand , Parenteral Nutrition, Total , Stress, Psychological , Transcutaneous Electric Nerve Stimulation , ZincABSTRACT
Benign fibrous histiocytoma is a common benign fibrohistiocytic tumor that's usually confined to the dermis. A 20-year-old female presented with a skin-colored, hard subcutaneous nodule of 1 cm diameter on her right flank. The histopathologic findings showed a well circumscribed, purely subcutaneous nodule composed of a fibrohistiocytic proliferation, and this was consistent with subcutaneous benign fibrous histiocytoma. We report here on a rare variant of benign fibrous histiocytoma that was confined to the subcutaneous layer without any epidermal and dermal changes.
Subject(s)
Female , Humans , Young Adult , Dermis , Histiocytoma, Benign FibrousABSTRACT
Becker nevus syndrome is a phenotype characterized by the presence of a Becker nevus in association with unilateral hypoplasia of the breast or other cutaneous, muscular or skeletal defects. We report an interesting case of Becker's nevus syndrome associated with fibrous dysplasia of the sphenoid bone, tooth abnormalities and facial asymmetry.
Subject(s)
Breast , Nevus , Phenotype , Skin Neoplasms , Sphenoid Bone , Tooth , Tooth AbnormalitiesABSTRACT
Milker's nodule is a harmless skin lesion that's caused by the paravaccinia virus (also called pseudocowpox virus), which is a member of the genus Parapoxviridae. It occurs worldwide, but it is prevalent only in individuals who are in close contact with cattle. We report here on a woman who presented with a dusky purpuric center surrounded by a white or gray ring and an outer red halo on the back of the right hand. Histologically, intracytoplasmic inclusion bodies were evident in the upper epidermis, and these revealed cylindrical virus particles on electron microscopy. Parapoxvirus was identified by polymerase chain reaction with using pan-parapoxvirus primer 1 (PPP-1) and PPP-4.
Subject(s)
Animals , Cattle , Female , Humans , Epidermis , Hand , Inclusion Bodies , Microscopy, Electron , Parapoxvirus , Polymerase Chain Reaction , Pseudocowpox Virus , Skin , VirionABSTRACT
Clear cell hidradenoma (CCH) is a relatively rare benign tumor that shows differentiation toward the structure of an eccrine sweat gland. The tumor masses are composed of solid areas and tubular lamina. Cystic spaces are often present and on rare occasions they can be of considerable size. The cystic variant of CCH is referred as solid cystic hidradenoma. We present a case of cystic clear cell hidradenoma that occurred on the abdomen in a 42-year-old man. The tumor contained a solid tumor of CCH encircled by a large cystic space, and the cystic space was lined by two to four layers of epithelium.
Subject(s)
Adult , Humans , Abdomen , Acrospiroma , Epithelium , Sweat GlandsABSTRACT
Renal cell carcinoma (RCC) is well known for its frequent metastasis and particularly to the lungs, liver, bones and brain, but metastasis to the skin is rare. We report here on a case of metastatic RCC in a 73-year-old man who presented with a 1.5 cm sized, moist, beefy-red and exophytic nodule on the scalp. The lesion had grown rapidly for 2 months and it clinically mimicked granuloma pyogenicum. A skin biopsy revealed a solid mass composed of clear cells with clear cytoplasm and oval hyperchromatic nuclei, and they were arranged in an alveolar pattern. As skin metastasis from renal cell carcinoma signals widespread systemic metastasis and a poor prognosis, clinicians should conduct a careful inspection of the skin of a patient with RCC and they should also have a high index of suspicion for finding a primary internal organ malignancy in the RCC patients who present with a skin lesion.
Subject(s)
Aged , Humans , Biopsy , Brain , Carcinoma, Renal Cell , Cytoplasm , Granuloma , Granuloma, Pyogenic , Liver , Lung , Neoplasm Metastasis , Prognosis , Scalp , SkinABSTRACT
Trichloroethylene (TCE) is a chlorinated hydrocarbon that is widely used as a degreasing agent in industry. Systemic absorption of this chemical can result in neurological, hepatic and cutaneous toxicity. Several cutaneous manifestations of TCE-exposed patients have been reported, including Stevens Johnson syndrome, subcorneal pustular eruption and generalized pustular eruption. We report here on an unusual case of TCE hypersensitivity syndrome in a 38 year old man after occupational exposure to TCE.